參考資料

1. Ruff JK, et al. (2009) Eggshell membrane: A possible new natural therapeutic for joint and connective tissue disorders. Results from two open label human clinical studies. Clinical Interventions in Aging 4:235-240.
2. Ruff JK, et al. (2009) Eggshell membrane in the treatment of pain and stiffness from osteoarthritis of the knee: a randomized, multicenter, double-blind, placebo-controlled clinical study. Clinical Rheumatology 28:907-914.
3. Danesch U, et al. (2014) NEM Brand Eggshell Membrane Effective in the Treatment of Pain Associated with Knee and Hip Osteoarthritis: Results from a Six Center, Open Label German Clinical Study. Jorunal of Arthritis 3:136.
4. NNT for glucosamine and chondroitin calculated from the GAIT study. (N Engl J Med 2006, 354(8): 795-808).
5. Ruff KJ and DeVore D (2014) Reduction of pro-inflammatory cytokines in rats following 7-day oral supplementation with a proprietary eggshell membrane-derived product. Modern Research in Inflammation 3(1):19-25.
6. Benson KF, et al. (2012) Effects of Natural Eggshell Membrane (NEM) on Cytokine Production in Cultures of Peripheral Blood Mononuclear Cells: Increased Suppression of Tumor Necrosis Factor-a Levels After In Vitro Digestion. Journal of Medicinal Food 15(4):360-368.